February 2, 2012 by dailybolusoflr
Steroids in Meningitis
Corticosteroids are considered part of the treatment to be considered for patients with presumed bacterial meningitis, although data is not conclusive.
Possible benefits include: reduced cerebral edema, decreased CSF pressure and decreased CSF lactate levels as well as potentially a shorter course of symptoms and decreased in long term hearing loss (found in infants and children)
Benefit is thought to be most seen in cases where H. flu is the etiology (children) and where S. pneumonia is the etiology (adults)
If used, the administration of dexamethasone should be given either 15 minutes prior to or concurrently administered with the antibiotics and then continued for the following 4 days at 6-hour intervals. Agreement that doses given over an hour before antibiotics are likely not helpful.
Ref: Rosen’s 7th ed