July 19, 2011 by dailybolusoflr
Bolus Use of Pressors
Two pressors come to mind when you think about bolus use- Epinephrine and Phenylephrine
Phenylephrine is the more commonly used agent- it is a pure alpha agent. Its onset of action is about 1 minute and it lasts about 20 minutes.
You can administer 50-200 mcg every 2-5 minutes as needed while you are attempting to get central access.
EMCrit has a good little blurb which I have cut and pasted below to show how to mix it up.
Take a 3 ml syringe and draw up 1 ml of phenylephrine from the vial (vial contains phenylephrine 10 mg/ml)
Inject this into a 100 ml bag of NS
Now you have 100 mls of phenylephrine 100 mcg/ml
Draw up some into a syringe; each ml in the syringe is 100 mcg
Linda Regan, MD FACEP
Program Director, Emergency Medicine Residency
Johns Hopkins Medical Institutions
1830 East Monument Street
Baltimore, MD 21287